Digital Kingdom

"What are the arrangements for today?"

As soon as Zhao Ziming got out of the elevator, the assistant held the folder and waited, and immediately followed the leader and began to report:

"The white cell laboratory sent a report, and you need to check it yourself."

"Got it."

"The notice about raising the salary levels of 12 people including Hu Zhihua, requires your signature."

"bring here."

"Mr. Liao Tianming, director of Qingdao National Laboratory for Marine Science and Technology, has made an appointment with you to discuss Fuxi's supercomputing lease."

"It's ten o'clock."

...

One by one, the to-do items were reported in order of importance. Zhao Ziming listened and processed them. In just a few minutes, all accumulated and appointment items were processed.

It's not that work efficiency is high. Many are just procedural matters. With Fuxi's intelligence, he can make his own decisions. Zhao Ziming's arrangement is only to maintain control and influence on the overall situation.

The use of power is one-minded.

Many things seem unnecessary but essential.

The two walked through the long corridor to the chairman's office.

As the supreme leader of the group, although Zhao Ziming has no important information, the office is also the most confidential place. No one can enter without his permission.

With Fuxi's level of intelligence, there is no need for pupil scanning, face brushing, stride measurement, and deportment monitoring. You must come in person or get authorized to enter.

Similar to a real guard but higher than the guard.

Zhao Ziming took off his jacket and opened the floor-to-ceiling windows. In the distance, the Huangpu River rushed past, giving him the feeling that the sky was broad and his heart was relaxed.

They boiled water and made tea one by one, and helped the leaders arrange their clothes by the way.

"One by one, trouble you."

Zhao Ziming returned to the computer and said casually.

"Leader, this is my job", smiled one by one.

"One by one, have you considered your future plans?" Zhao Ziming took a sip of tea.

One by one was a little at a loss, what do you mean, I was fired?still is……

Zhao Ziming continued, "You can't always be an assistant for me. You can't learn anything after a long time, which is not conducive to personal growth. I remember a girl who entered the company with you and was about to be promoted to a department deputy. ?"

One by one took the words: "Gu Pan."

Zhao Ziming nodded: "Yes, I think she is on the list of promotion this time. As time goes by, the gap between you will get bigger and bigger."

Because Zhao Ziming abolished the position of "secretary", Fuxi had traditionally done it for the hot position. Many of the powers of the chairman's office were weakened, and they even degraded to assistants. They did some simple communication and coordination work, and the number of people also increased from the peak. More than 30 people have been reduced to more than 10 today.

One by one he bit his lip without speaking.

Zhao Ziming smiled: "The future trend of the company is to reduce the number of cadres sent, and try to promote from the front line."

As the saying goes, the prime minister must start in the state and county, and the fierce general must start in the army.Reducing the number of cadres assigned can prevent laymen from leading experts and encourage a down-to-earth style.

One by one, his eyes widened, "Leader, I don't have much ambition, and I am fine now."

Zhao Ziming heard, "That's it, it's actually fine."

Explained one by one: "You can arrange any job for me, but I don't like being an official. The responsibility is too great and it will keep me awake all night."

Zhao Ziming laughed, "Oh, well, if you don't want to, then stay in the office all the time, but don't blame someone for privately saying that you serve tea and pour water."

When I saw it, I breathed a sigh of relief and jumped for joy, "What's wrong with pouring tea and water, I like to pouring tea and water."

Zhao Ziming looked at one by one, and the scene of the first meeting came to mind, but Li Rongrong filled his mind at the time, and didn't pay much attention to a big beauty. "One, is there still contact with Rongrong now? "

One by one looked surprised, and then a little embarrassed, "So you remember it all."

She always thought that Zhao Ziming had no impression of the past, and she felt quite uncomfortable.

"Haha, how could I forget, I remember that Hua Yuancheng had been dedicated to you at that time, what happened to this kid now?"

"It's still the same, I don't pay attention every day", and I feel a little headache to mention each one.

Zhao Ziming couldn't help smiling when thinking of Hua Yuancheng's second.

After looking at the boss's face one by one, he said carefully, "Sister Rongrong, there are few contacts, she is usually too busy."

In fact, after the fellowship meeting, the two of them had been in contact for a period of time and their relationship was quite good. Later, Li Rongrong saw that one pair of boyfriends did not appraise high, so she became a little angry, and one of them had tempers. The two froze and slowly stopped talking .

Zhao Ziming nodded, "Yes, she has a lot of things, but she can come out to get together if she has nothing to do. After all, acquaintance is also fate.

One by one agreed: "Yes, I will contact Sister Rongrong these days and have a meal together."

"Well, it should be."

"Leader, it's okay I'll go out first."

"Okay, go ahead." Zhao Ziming sat down and looked at the camera.

Turn around and go out one by one.

The smart terminal automatically recognizes the face in front of the screen, without unnecessary operations, and the computer is already turned on.

Zhao Ziming glanced at it and found more than a dozen unread messages:

The report from the "White Cell" laboratory has the highest priority and ranks first.

Followed by:

Financial report analysis of each subsidiary.

"Fuxi" daily situation report.

Network public opinion monitoring.

Investigation of key areas.

...

Zhao Ziming first clicked on the laboratory report, the content is not much, you can see the bottom at a glance:

The blood team led by Xie Zhenting completed major technical research and successfully developed implantable pharmaceutical cells.

For a while, Zhao Ziming was a little unbelievable. Although he didn't understand the specific technology, he was marked as a major breakthrough. One can imagine the value of it.

First, the Gao Yongyan team completed the epoch-making product "Direct Dreamland" bracelet, and then the white cell laboratory made a major breakthrough. The good news one after another, and then the He Gan team's "brain portal" system is mature...

Could it be that with the arrival of artificial intelligence "singularity", all industries are about to usher in a big explosion?

This is not impossible!

Thinking of this, Zhao Ziming got up and went straight to the White Cell Laboratory.Standing in front of a full-length mirror, I drew a pattern casually, a few lights flashed, the mirror quietly opened a door, people walked in, and the office returned to its original state.

For confidentiality, the entire building, except for Zhao Ziming's office, which can directly lead to the underground laboratory, has only one exit for the "white" project team.

Outsiders don't even know the "white" and "blue" laboratories. On which floor, the digital building has undergone a large-scale transformation since it was acquired as a whole, and the original layout has long been completely changed.

The elevator is equipped with the corresponding gravity adjustment technology. Even the people in the laboratory think that they are working on the ground, but do not know that they have gone deep into the underground ten floors.

Xie Zhenting, who got the news, had been waiting for a long time. As soon as they met, they began to report the situation.

Since the last time that pluripotent stem cells successfully induced functional 3D human vascular network organoids, with the help of supercomputers, the vascular research project team has succeeded in researching implantable pharmaceutical cells before MIT.

Just listen to the name. This cell means that once you get sick, the doctor can transplant living cells into your body, turning these living cells into a "drug factory", releasing drugs regularly and quantitatively to treat you, eliminating the trouble of taking medicine. .

At first glance, it seems useless, just take a medicine, why is it so troublesome?

Xie Zhenting gave an example:

"There are many diabetic patients who have to pierce their fingers several times a day to measure their blood sugar levels to determine how much insulin they need to inject. This is a very torturous thing. Over time, the muscles in the stomach will become stiff.

If the pancreatic islet cells that normally produce insulin can be implanted in the patient's body, this tedious process can be avoided.These islet cells automatically release insulin based on the body's blood sugar status."

Zhao Ziming nodded. This idea is very good. Someone must have come to study it a long time ago. He asked, "Where are the difficulties before? Why hasn't it been successful?"

Xie Zhenting led the boss to the door of a laboratory and gestured to look inside. Several staff members were busy:

"Implantation is not that simple, because transplanted cells will be interfered by the autologous immune system, and the body's immune system will naturally reject foreign cells and prevent them from functioning. In this case, the use of inhibitors cannot be used to suppress immunity. Turning off the system, in that case, the body will lose its protective barrier, and the gain will outweigh the loss."

Zhao Ziming thinks about it, it is indeed like this. Xie Zhenting's eloquence is very good, and the words are simple and easy to understand. He basically understands it.

"Then how did we solve this problem?"

"We make the transplanted cells "invisible" in front of the immune system, so as to avoid being recognized and attacked." Xie Zhenting smiled. In order to let the boss know the hardship and the great significance, he continued,

"In the past few decades, scientists have experimented with many methods. The closest thing to success was to enclose cells in a semi-permeable protective membrane to prevent the immune system from attacking.

"But in the same way, the immune system treats the protective film as a foreign substance, and grows fibrous scar tissue around the capsule. Slowly, they will cling to the cells and block the entry of nutrients. Finally, the cells will be stuffy. dead."

Zhao Ziming asked with interest, "Then our method of invisibility has similar flaws?"

Xie Zhenting is very confident: "After we developed and screened tens of thousands of materials through Fuxi Supercomputing, we chose a chemically modified substance called "alginate gel" to seal the cells in this gel. , Can achieve the purpose of "stealth", thereby deceiving the immune system."

Supercomputers provide drug candidates for clinical trials through virtual compound screening, design and optimization of compounds, and modeling of absorption, distribution, metabolism, excretion and toxicity.

Zhao Ziming asked, "What do you say about animal experiments?"

Xie Zhenting: "The performance is perfect. The pancreatic islet cells are sealed in a gel and implanted in a diabetic mouse. After evading the immune system, these cells immediately begin to work to produce insulin in response to changes in blood sugar."

Zhao Ziming asked: "Are there any side effects?"

Xie Zhenting was very excited, "No, it can help the mice continue to control their blood sugar levels for as long as a month. During this period, the mice’s immune system did not produce any rejection reactions, according to Fuxi’s supercalculation Modeling, you can be sure that there will be no impact during implantation."

Zhao Ziming was very satisfied, "Okay, okay, it's really a gospel for people with diabetes, have you started human experiments?"

Xie Zhenting nodded: "Fu Xichao has saved us 90% of the workload. If you have no objection, I would like to apply for the human experiment immediately. Although it is a bit hasty in terms of time, the results of the experiment are very Perfect, the relevant experiment records are complete and detailed, and it can deal with all inspections and carry out the next experiment, of course."

Zhao Ziming naturally knows the great role of supercomputing in pharmaceuticals. When the laboratory was established, several people were configured with higher usage rights, but he did not expect results to be produced so soon.

Under the guidance of Xie Zhenting, Fuxi classifies massive amounts of text data, provides rapid analysis to discover drugs, and tests hypotheses by classifying large amounts of laboratory data, clinical reports and scientific literature. It can be said that a computer is on top Ten teams.

One will be worth a million divisions!

"It's okay if you decide. Zhen Ting will act for the country and the people. Can it be applied to other diseases besides diabetes?"

Xie Zhenting replied: "We have carried out research on glaucoma and Parkinson's disease at the same time, and the effect is remarkable. In the next step, implantable cell therapy will be implanted in artificially modified cells to achieve more precise drug control and release."

Zhao Ziming nodded and smiled.

Over time, "drug factories" like this that can be implanted in the body will have more and more types and more and more uses. The treatment of many diseases will bid farewell to the cumbersome medication process.

Even one day in the future, even if you are sick, you don’t need to worry about everything. The implanted cells will be like a "housekeeper", feeding you the medicine on time and in the amount. All you have to do is to recover.

As Xie Zhenting took a look at the work in progress, Zhao Ziming was extremely satisfied. The implantable pharmaceutical cell is just one of the representatives. It is far from explaining the true strength of the laboratory, from gene editing to cancer vaccine, from cloning technology to Human microbes, from synthetic biology to reusing drugs, are covered by "white" laboratories, almost all of which are at the world's leading level.

With the help of Fuxi Supercomputing, a lot of labor was saved, and even the shortage of manpower was alleviated. The application of automated robots made the experiment progress at a rapid pace.

Tireless, no mistakes, and all records can be traced back. Under these conditions, Xie Zhenting simply split his hands into nearly ten project teams, each with one or two people, and started work at the same time, which not only greatly stimulated the enthusiasm of his staff, but also The worry is in a rush, and it doesn’t appear. It’s no surprise that progress is advancing by leaps and bounds.