Digital Kingdom

"Mr. Zhao, we have accumulated more than 20,000 genetic elements since 2003, and we have also designed a set of standard assembly processes that can assemble these genetic elements like Lego." Ye Zimei is afraid that Zhao Ziming will see them as Those who take advantage take the initiative to expose their cards.

Zhao Ziming was puzzled, "Miss Ye, please forgive me for being direct. I don't think this is a big breakthrough. These genes are all artificial, and some people have studied them before. What you do is just collect the genetic elements scattered in various laboratories. stand up."

A trace of shame flashed across Ye Zimei’s face. He didn’t expect that the other party’s eyes were so small that she could hardly come to the stage. “Mr. Zhao said that, it’s just a layman, let alone other things, our component library has been accumulated for 15 years, although Not comparable to foreign countries, but it is second to none at home."

"Oh," Zhao Ziming gave no response.

Ye Zimei couldn’t help but continue, “This element library is like a big dictionary. What function each gene element has is originally only in the hands of the researcher. With the big dictionary, this knowledge is standardly summarized in the big dictionary. In the dictionary, anyone can look through it."

Zhao Ziming thought for a while, isn't this just an index?However, it will take a lot of time for him to start a new one. From this point of view, the other party is not worthless.

Ye Zimei continued, “Just like Professor Ye’s insulin research, the switch element it replaced is actually from a type of bacteria. This bacteria needs to respond to light because of its photosynthesis. These two studies are in In the past, I couldn’t get it done, but with this dictionary, it’s much easier to find the components you want."

Zhao Ziming did not speak, but Wang Zixue saw the situation and took over, "To a certain extent, the establishment of a component library is equivalent to standardization and refinement, with a clearer division of labor. Some of them specialize in analyzing the functions of genetic components and continue. Do scientific research, and some people use these genetic elements to assemble new lives."

You can ignore the leaf frieze, but Wang Zixue's face must be given. Not to mention the in-depth cooperation between the two, at the key node of the brilliant listing, billions of contracts are also a big variable.

Wang Zixue himself is also worthy of respect. He has a lot of praise for Zhao Ziming, and he has the style of a big brother.

"President Wang, are you going to get involved in this?"

Wang Zixue was stunned. He didn't expect the other party to be so direct, and then he smiled, "You tell me, gene editing and biosynthesis have a bright future. They are rare variables of the times that can keep pace with artificial intelligence. We Huatai have invested a lot in recent years. For start-ups, I want to wait until I retire, maybe just focus on this and do little things."

Zhao Ziming nodded, and Ye Zimei took the words: "Biosynthesis and gene editing are not only the frontiers of science, they are also hot in the eyes of capital. Technology giants like Bill Gates, Sergey Brin, and Peter Thiel are all working in this field. Investment, technology giants such as Microsoft and Google are also deploying in this field. Jobs said that the biggest technological innovation in the 21st century is the combination of biology and engineering."

Zhao Ziming looked at each other, "How does Ye always plan to cooperate?"

His psychology has been touched. In less than 20 years since its birth, this young discipline has 5 listed companies. Last year alone, the amount of venture capital in the field of synthetic biology reached 1.8 billion U.S. dollars, an absolute prospect. huge.

"We provide resources, and you provide technology, each holding 50% of the shares, sharing benefits and risks." Ye Zimei smiled slightly, as if the spring snow melted.

Zhao Ziming shook his head, the lion really opened his mouth.

Ye Zimei calmed down, "What does Mr. Zhao mean?"

"Give you 10%, the first phase of the research funding of no less than 100 million yuan will be provided by you, and then half of the funding will be provided by the two companies." Zhao Ziming looked at her.

Sure enough, the lintel was so angry that the towering chest was constantly rising and falling, almost unbearable anger, to gush out, if it wasn't for a little ladylike demeanor, he immediately shook his face and left.

Wang Zixue frowned and quickly stretched out, "I don't know yet whether your laboratory's progress has made a major breakthrough."

Hearing the words, Ye Zimei reacted instantly. No matter how arrogant Zhao Ziming was, he would not offer such conditions that were almost insulting and charity.

Zhao Ziming did not irritate the other party, he was a little disappointed, and there were exceptions to his mindlessness. "Mr. Ye wants to work with us, probably because he valued the accumulation of the digital group in artificial intelligence."

"It is a win-win cooperation."

Zhao Ziming smiled and continued, “If you want to design a protein from scratch, suppose there are only 100 amino acids that make up it, and there are as many combinations as 20 to the 100. This number is beyond imagination. With more experiments and more tests, you may never find the correct assembly plan. This requires combining computer science and using computers to simulate life."

Ye Zi's frieze was expressionless, and his eyes revealed the meaning of "what is it?

Zhao Ziming continued, “We have made breakthroughs in the research of life modeling. A group of real multicellular organisms have been simulated in the computer. The cells can not only grow and reproduce, but also transmit signals, and can edit cells at will. To observe how cells and living organisms change in the genes in the past, it may have taken 10 researchers a year of work, but now it’s done in a few minutes by simulating the data."

Ye Zimei was surprised when he heard this. Although he had overestimated the technological accumulation of the Digital Group, he did not expect it to be far behind.

In her prediction, the Digital Group should almost be able to successfully simulate a cell with a computer. Who knows to go a step further and simulate a complex multicellular life body.

Even if the actual process is highly abstracted, this simulation still requires strong computing power, which is not a simple addition.

Compared with a single cell, in addition to the metabolism and regulation at the cell level, a multicellular organism must also be able to handle the interaction between multiple cells. The detailed regulation will be extremely complicated, involving chemical stimulation, concentration gradients, and fluid mechanics. And many other factors.

"Even so, your conditions are too harsh," Ye Zimei thought for a long time, struggling to say.

Zhao Ziming laughed, "It has always been you and me when it comes to cooperation. Since Miss Ye is unwilling, then forget it. There is no reason to buy and sell."

Wang Zixue took the words, "I think it's better to find a time to sit down and talk slowly. Such a big thing needs more communication."

Zhao Ziming shrugged, "I have no problem here, as long as Miss Ye doesn't dislike it."

"What do you dislike?"

Ye Zimei suddenly thought of the other party's bad reputation, his pretty face blushed, regretting a little bit in his heart.

The hole has already come, and if you continue to contact it, I am afraid it will be even more unbearable.

"I also just learned that someone was talking nonsense and apologized for the trouble caused to Miss Ye," Zhao Ziming continued.

The leaf frieze was speechless.

When Wang Zixue saw this, he found an excuse to leave. Although he liked to make jokes, he was winking and wise. It was too stupid to know that the private affairs of two people were involved.

"Miss Ye, please sit down," Zhao Ziming greeted.

Ye Zimei's face changed a few times, and he sat down.

"Speaking of which, it is the first time that Miss Ye and I have met today. If there is anything offended, please forgive me." Zhao Ziming changed his aggressive attitude and was polite.

A trace of shame flashed under Ye Ye's heart, the other party really didn't open which pot to lift which pot.

"It's nothing."

"Miss Ye really has a lot of adults," Zhao Ziming admired.

"Those messy things, I never took it to heart." Ye Zimei cleared up his mood and returned to the posture of a strong woman.

"But speaking of it, I still have to apologize to you", Zhao Ziming was a little embarrassed.

"what?"

Zhao Ziming: "I just asked someone to check it. The latest rumors may have been directed at me. Miss Ye is considered a disaster."

Ye Zimei frowned, "Who is so boring."

Zhao Ziming: "I don't know for the time being. There have been a lot of rumors recently. Almost all the heroes are me, and there is only one time about Miss Ye. I should be involved."

Ye Zimei blushed, and she naturally knew how unbearable the rumors were, otherwise she wouldn't be blamed on Zhao Ziming for an unnecessary charge.

What to play with dragons and phoenixes, double phoenixes vomiting beads, dragons and phoenixes are prosperous, phoenix dances for nine days, it is extremely nasty.

"Are you not angry at all?"

Ye Zimei looked at Zhao Ziming calmly, a little puzzled.

"The so-called clear people are clear, and the muddy ones are turbid. It's not worth being angry about this kind of thing. If it wasn't for Miss Ye's anger this time, I wouldn't even pay attention to this kind of thing," Zhao Ziming said lightly.

Ye Zimei was not only a little ashamed when he heard it.

Naturally, she didn't know that the other party had more shai, no worries, more debt, no itching, besides, there were so many fancy things arranged, few fictions.

Zhao Ziming continued to pretend, "Someone has fabricated this kind of thing before, but no one has ever come to the door, and hasn't paid much attention to it. This time I realized that it caused a lot of harm to the woman, which really makes me ashamed."

The more Ye Zimei listened, the more embarrassed he became. He felt that he had made a fuss. The anger towards Zhao Ziming disappeared, but a trace of guilt arose.

Speaking of which, she is also the head of a listed company. She is not to be disturbed by trivial matters, but she is rather jerky in matters of men and women. She is still in her thirties and is still alone. She has always kept herself clean. Hearing someone arranging her gossip vividly, it is very It is embarrassing.

As soon as Zhao Ziming looked at the other person's look, he understood his thoughts and smiled, "As the saying goes, you don't know each other if you don't fight. It's a blessing in disguise to have the opportunity to meet Miss Ye this time."

"Just call me Amy," Ye Zimei answered.

Zhao Ziming pushed the boat along, "Amy, although I am very happy to meet you, I have one thing to say about the conditions for cooperation. I hope you can understand."

Ye Zimei didn’t feel surprised at all when she heard the words. She was originally in business. If the other party has a few words or two, she changes her position and forgets her parents when she sees a beautiful woman. Then she has to reconsider the possibility of cooperation. After all, the real money invested is not a reliable person, and it is easy to get rid of it.

Without waiting for Ye Zimei to say anything, Zhao Ziming continued, "If you want to involve Mr. Wang in the project, I will not object, but the shares can only be divided from your 10%."

"This", Ye Zimei was a little embarrassed,

The prerequisite for cooperation not only cannot be modified, but is even more demanding, which makes her unable to accept it for a while.

As soon as Zhao Ziming looked at the other person, he knew that he had guessed the opponent. Wang Zi learned to jump up and down, working hard and busy. He must have something to do. Just as an introducer, he wouldn't have so much motivation to match this matter.

"When I talk about things, I have always been very direct. I don’t want to make high prices. You come and go, and we fight over and over again. The conditions are here. If you can accept it, continue to talk about it. If you can’t accept it, everyone is still a friend. If you have the opportunity to cooperate again," Zhao Zi Ming stated his bottom line.

Ye Zimei hesitated, don't accept it, the other side's technology is unique in the world, and there will be no competitors at home and abroad in the short term, accept it, the conditions are too harsh, it is simply kneeling for cooperation.

I donate people, money, and resources, and the final research results account for only 10%. I feel aggrieved to think about it.

Zhao Ziming looked at the other party's uncertain face, and forbeared the final conditions.In his plan, 10% of the shares only enjoy the right to income, without any other rights.

It seems very demanding, but the core technology is in hand, and Ye Zimei's joining, but it saves him a little time and energy, it is not necessary for her.In this case, it is natural to chase the poor.

"I need to go back and think about it, and then give you an answer." Ye Zimei finally resorted to dragging words.

"Okay", Zhao Ziming was not surprised by this answer. When it comes to an investment of hundreds of millions of yuan, the board must go through the board of directors. Even if Ye Zimei agrees, the resolution will be invalid without the authorization of the board.

"One more thing, I can tell you in advance." Zhao Ziming smiled, the three-dimensional features are full of masculine charm under the light.

"what?"

"You know that the structure of proteins is very complex, and most of the time the predictions are not accurate. Directed evolution of proteins requires a lot of trial and error. We used artificial intelligence to train the neural network algorithm with thousands of known protein structures, and then it took ten minutes to predict. The first protein structure, although there is still a certain gap from fully predicting the function of the protein, but you know", Zhao Ziming gave an anise.

I believe that once this news comes out, it will be difficult for the other party to escape from the palm of his hand.

Sure enough, Ye Zimei seemed to be frightened when he heard the words, and it took a long time before he replied "thank you".

Outsiders don’t know what it means. As an expert in this field, Ye Zimei knows exactly what directed evolution protein means.

Accelerate evolution and obtain functions that nature does not have.

Gene mutation is very slow. On average, it is estimated that a random error occurs every 1 billion bases of DNA copied.If you rely on natural genetic mutations, it is almost impossible to get a new function or new trait of a certain organism immediately, and "accelerated evolution" is to artificially change these two conditions, and directed evolution protein is an important direction among them.