Great Power

The official name of the blue pill is Sildenafil, which is translated into Chinese as Sildenafil. The molecular formula of the white crystalline powder is C22H30N6O4S. It was originally a medicine for the treatment of cardiovascular diseases. I don’t want to really promote blood movement. Contrary to the researcher's wishes, he went to the cavernous blood vessels, so the commercial name Viagra became the "Viagra" passed by word of mouth.

Not to mention that Zheng Jianguo can't remember the synthesis process at all. He doesn't remember the n-propylpyrazole, ethyl carboxylate, and dimethyl sulfate in the materials used. Of course, these things are not important to him. Not big, because these are all processes, even after the white crystalline powder of sildenafil is extracted, the purpose of sending it into the human body is to get the result: NO!

Putting these two letters together is not the meaning of opposition in English words, nor the ordinal number of the ranking, but the chemical formula of nitric oxide.

As a nitrogen oxide compound, this thing is a toxic substance under normal conditions. Because of its own free radicals, it will react after encountering oxygen. The result of the reaction is NO2 and nitrogen dioxide.

And if you encounter water at this time, then nitric acid will be formed. At this step, congratulations on your synthesis of strong acid!

It is such a toxic thing no matter how it looks, but it is the only reason why countless men like the blue pill. According to Zheng Jianguo’s memory, doctors used nitroglycerin to treat ischemic heart disease for this reason. He also knew that the reason why nitric oxide can treat ischemic heart disease is because it can expand blood vessels.

Since the blood vessels can be expanded, the blood vessels leading to the cavernous body are also blood vessels, so the original single-plank bridge instantly expanded into an airstrip——

In fact, Zheng Jianguo also knew that this thing can promote blood circulation in the brain, regulate the secretion of human insulin, reduce blood viscosity, smooth muscle relaxation, immune response, cell apoptosis and synaptic information transmission, etc.

Of course, at this moment, Zheng Jianguo went back to when he saw the graphite powder on the tape, that is, he knew that he didn’t know the reason, but it was a little different from graphite powder. Doctors used nitroglycerin to treat heart disease. The history can be traced back to 1878, that is, doctors did it a century ago.

However, in the past century, Zheng Jianguo does not believe that no doctors have studied this phenomenon. In other words, it is impossible to be in a dark state under the light like his previous Helicobacter bacteria. The greatest possibility is due to electronic technology. If you can't see the mechanism of action, you can check the paper in the library if you want to confirm the correctness of this idea!

As the world’s top medical school, the library of Harvard Medical School collects all the official academic journals issued by the world. The huge collection allows the whole school to keep abreast of the latest developments in various medical disciplines, which is what Zheng Jianguo wants. The journal where nitric oxide is most likely to appear is the journal Blood Vessels named after the medical profession.

With the development of science and technology, the division of labor has become more and more detailed. Although the medical journal "Blood Vessels" is not as famous as "Lancet", it is all the doctors in the refined field of vascular medicine. Our holy places, the same as those published above, are also the latest research in the direction of vascular medicine.

After more than two years of experience in searching the literature, Zheng Jianguo chose to start with the latest issue of "BloodVessels" journal, and since his current two professional fields are very different from cardiovascular medicine, plus Because of the ghostly fear of being targeted by the FBI who does not know where he is, all he can do is to pretend to be inadvertent and start to understand, so he didn’t find what he wanted until the day before Christmas Eve: How endothelial cells cause vascular smooth muscle relaxation "——

""BloodVessels" March 1979 issue?"

Quickly glanced at the cover, Zheng Jianguo knew that this was what he wanted, but after he read the above report, he found that this paper came from the well-known Furchgott laboratory. The reason why it is said to be small and famous. Based on his current vision, in fact, the Furchgott laboratory, as a professional laboratory in vascular medicine, has been conducting research on this phenomenon for 25 years, and this has also made Zheng Jianguo start to face his own work. By.

Zheng Jianguo is a fake researcher. His essence can only be regarded as an academic thieves inferior to Nong Shaoshan. At least Nong Shaoshan is really through his own hard work and study, although he has reached the pinnacle of his life in a fraudulent way. It was only caused by the opponent's low professional ethics, and Hong Guoguo's low moral character, Zheng Jianguo, who stole the academic achievements of others.

One is low professional ethics, and the other is low moral character. This is a thorn buried in Zheng Jianguo's heart. Especially at this moment, I saw that it had been 25 years for this laboratory to touch the shadow of NO. He had already thrown it away. The conscience seemed to have recovered when he reached the sky, and he put the periodical on the shelf, watching "BloodVessels" with dark eyes, and fell into a battle between heaven and man.

Zheng Jianguo knows that endothelial cells cause vascular smooth muscle relaxation because of the effect of NO. At this time, people have not found NO, even endothelial relaxing factor. He can use the excuse of discovering Helicobacter to find something for himself. The reason-just when this thought flashed through his mind, two completely different figures appeared in his mind.

On one side, there is a figure with a black cross: "You have stolen Helicobacter and graphene. This NO is just a profitable invention. You discovered it with your conscience? You don’t want money anymore? There are billions of dollars a year. Watching people make money away?"

On one side, there is a figure holding a white shield: "You have also done experiments, you have cleaned the laboratory, you have tore off the tape, and you have washed the reagent bottles, and you also buried yourself in the cold rain with literature to warm yourself, Furchgott experiment The director and experimenter in the room have been unknown for 25 years. Do you know how many 25 years there are in life?"

The voice of the black fork became louder: "You know what they found is that they can't enjoy it at all. The pharmaceutical factory will not give them even a cent of profits. All the profits of NO are used to bribe and consolidate the hegemony of the pharmaceutical factory. If you take this invention now, at least you can use the identity of the discoverer to share a cup of pie with the pharmaceutical factory—"

Bai Dun’s voice became smaller: "You are a researcher, at least you are a researcher in the eyes of the people next to you. You know the degree of criticism of researchers. They only have their heads in their 60s or 70s at a young age. Bright forehead, most of their families are unfortunate. They are all slaves, slaves who can't see their heads at a glance—"

The voice of Hei Cha’s voice was loud and loud: "You can help domestic development if you get the money. You can use this money to help countless people in the Republic, hundreds of millions every year—"

The figure of Bai Dun opened his mouth wide, but couldn't make a sound. All that was left was his mouth: "Don't—"

"Hi~"

Just as the figure holding the black cross showed a brilliant smile, a familiar voice appeared out of thin air, and the figure of White Shield showed a triumphant smile after it disappeared. Zheng Jianguo turned his head and looked at Ur, who was full of curiosity. Lika, nodded: "Hi, Ulrika~"

"Well, Zheng, what are you looking at? I look from behind as if you are from a distance, but here seems to be the area of ​​vascular medicine—"

Ulrika’s brown eyes scanned the magazines on the shelf, especially in the several magazines on vascular medicine that Zheng Jianguo had previously stared at. She shrugged and said, “Tomorrow is Christmas Eve, do you have a place to go? , Why don't you come to my place to play, now the research progress is not so fast, we decided to take a good rest, you can also drink now——"

"Well, I'm sorry, I already have a date, and I will be on a plane to Washington, you should relax—"

Zheng Jianguo's eyes scanned Ulrika's three-dimensional face, and the figure holding the white shield in his mind shouted loudly at the same time: "You are now the discoverer of graphene and Helicobacter. If you find NO again, This will bring you unforeseen consequences, at least you can't explain how you suddenly crossed the border to vascular medicine.

Now Ulrika has doubts about you!If the FBI asks her about your performance, you will be targeted by the relevant departments in the United States!And the discovery of NO only makes your money a little bit more, but are you short of money?Do you think the hundreds of millions of dollars you get every year are worth a lot, or are you likely to become a guinea pig after being targeted?"

"This is greed and vigilance—"

In an instant, Zheng Jianguo made a choice. The mind blinded by greed returned to normal under the vigilance. When he suddenly felt chill on his back, Ulrika had already noticed his strangeness: "Zheng, you don’t Comfortable?"

"It's a bit. I just felt a bit dull. It looks like I'm going to have a checkup, Ulrika, I'm leaving now."

Waved his hand and nodded, Zheng Jianguo turned and walked out towards the library. The Ulrika who was behind watched his back disappear, then turned to look at the periodicals on the bookshelf, and reached out to touch the "BloodVessels". The magazine appeared suspicious: “Why do you suddenly start to pay attention to vascular medicine? Has he already made new discoveries? This requires Charlie to check Zheng’s medical examination results and see him How many points did you score on the blood vessel test—"

At this moment, Zheng Jianguo could not know what Ulrika thought. He walked out of the library and looked at the sunny sky. The blue appearance did not look like a winter sky at all. He was disturbed by Ulrika before. Er's mind has completely recovered his clarity. Just as the vigilance in his heart said, he is now holding the two world-renowned discoveries of graphene and helicobacter, and then the blue pill of NO is integrated. This superimposed effect It's too dangerous-life is precious, and freedom is more expensive. This is an old saying!

Of course, the reason why Zheng Jianguo completely abandoned NO is because it is a bit too far from his Helicobacter. After consulting the literature during this period of time, he found that the previous idea of ​​NO was really taken for granted, not to mention the need to find NO. The mechanism of action, just 25 years of research in Furchgott laboratory scared him.

If the mechanism of NO takes 25 years to discover, Zheng Jianguo would not waste precious lives on it even if he was killed, although he vaguely felt that the difficulty of this thing was so great, it was worth it. A Nobel Prize is right-

Zheng Jianguo didn't know that his idea was right, and the discoverer of NO really won the Nobel Prize in Physiology and Medicine.

First it was dangerous and then it was too difficult. Zheng Jianguo had completely given up NO at this moment. Of course, he was not without gain in the library during this time. After getting off the plane that night, Zhao Liangliang picked him up from the embassy. After going through the phone to China, he said: "Teacher, I asked Mr. Wei Jianran to forward the "Journal of Molecular Biology" to you, right?"

"I received it, but I saw that the research in it is not of great value. The reference from 1971 to the present is greater than the actual meaning, of course I translated it out, and it is also good for students to refer to——"

Professor Ye Minde’s voice is a bit distorted, and I don’t know it’s the voice of the other party, and he said it hoarsely. Zheng Jianguo also smiled brightly: "Then you should remember that there is an article by Professor Clap too—"

"I remember, it was an article about the use of double primers to repair and replicate DNA. This was discovered by Klepp in 1969, and he also gave a lecture at a high-level conference—"

Ye Minde on the other end of the phone quickly beckoned to Tao Ye next to him. The latter quickly took the stack of manuscripts in front of him, quickly turned to the article page about Klepp, and looked at the regular script on it and said: " Well, he also wrote about the test process—"

"Teacher, you know that you want to tear one million layers of graphite, and you only need to fold it in half with tape 20 times, right?"

Zheng Jianguo’s voice was also distorted. Ye Minde, who was wearing reading glasses and full of silver hair, was taken aback, and subconsciously said: “Jianguo, you are a good student with keen observation. The same is true for the graphite layer of Helicobacter. I’m all fortunate that you didn’t hit your dedication to research at that time, so you would miss Helicobacter like other students and researchers who succumbed to authority--"

"Teacher, I am not talking about my achievements in Helicobacter and graphite layer. I am not showing my merits to you, let alone accusing you of making a decision that is indistinguishable from all the teachers. In fact, I need to thank you for this. You, Xiaoli said that you accepted me, a somewhat off-putting graduate student, and told Dali that it was the Helicobacter that was discovered after using your pension funds. My gratitude to you is unforgettable--"

Zheng Jianguo on the phone was extremely sincere, but when these words reached Ye Minde’s ears, he understood that the call was not as easy as in the past. This guy called himself to talk to himself: " Okay, well, there are no outsiders here, so Tao Ye is by the side. If you have anything you want to say, just say--"

"Teacher, I have an idea."

Zheng Jianguo glanced at Zhao Liangliang, who was playing with a Zippo lighter next to him, then glanced at the front desk lady in front of him, and said into the microphone: "It’s the same as tearing up a million layers of graphite by tearing 20 times. According to Professor Pu’s test method, I calculated that the DNA obtained in each cycle is twice that of the previous cycle. Then the DNA can be amplified 1000 times after 10 cycles, and 1 billion times after 30 cycles. !!!"