Hello, Mr. Major General

Lu Jin came to his experimental platform and cut alleles from the DNA fragments of Qin Yaoguang and Wen Shouyi for verification and comparison.

From the common sense, when the parent-child relationship of DNA identification is excluded, the accuracy rate can be 100%.

In other words, when the identification of two people is not related by blood, it is 100% accurate.

But to determine that there is a direct parent-child relationship between the two, the accuracy rate is only 99.99999%.

The nine after the decimal point can vary according to the number of alleles to be intercepted.

However, under normal circumstances, when the accuracy of determining that two people have a direct parent-child relationship reaches 99.99%, it can basically be determined that the two are directly parent-child.

The DNA tested by Lu Jin for Qin Yaoguang and Wen Shouyi was the entire sequence.

This is not only a sequencing that ordinary people can't afford, but even many people with a net worth of millions may not be able to afford it. Of course, it's not a big deal here.

He tested the entire sequence, and the intercepted alleles were as diverse as possible. Therefore, the accuracy of the parent-child relationship he tested was the highest even if it was less than 100%.

Run electrophoresis before the test. Simply put, it is to let the DNA double helix structure "swim" under a certain voltage. The DNA fragments with different functions "swim" at different speeds, so that different DNA fragments can be separated.

Then intercept alleles, and then use the software to analyze and compare.

Lu Jin completed a whole set of procedures, and Gu Nianzhi watched it with gusto.

Although she can't understand those pictures and data at all.

In order to strive for accuracy, Lu Jin spent half an hour using software to analyze and compare the intercepted allele fragments.

Finally sighed, "...They are really a biological mother-daughter relationship."

Gu Nianzhi: "..."

She was a little at a loss at the result.

She was mentally prepared, but when this prediction was confirmed, she felt incredible.

"...Qin Yaoguang and Wen Shouyi?! Are they really biological mothers and daughters?!" Gu Nianzhi was extremely surprised, "It must be a surrogacy? But why did she put Wen Shouyi in the Qin's orphanage? Later, she let Wen Da have Couple adoption?!"

Lu Jin nodded, "Surrogacy must be the only explanation. But why Qin Yaoguang put Wen Shouyi in the orphanage, this can only ask Qin Yaoguang."

"...But do you think she can tell the truth?" Gu Nianzhi said quietly, her eyes dark to the bottom.

Lu Jin said seriously: "She probably won't. But I think this is her privacy, do you have to ask?"

"Yes." Gu Nianzhi nodded cautiously, "This is related to the integrity of the court's evidence chain. ——Dad, you know Qin Yaoguang well, can you reason about why she did this?"

When Gu Nianzhi talked about legal terms, Lu Jin was just like Gu Nianzhi heard high-energy physics terms, his eyes circled.

He said dizzyly: "Actually, I don't know much about Qin Yaoguang. But after so many years of experimenting with her, I basically know her attitude toward genetic research."

"What attitude?" Gu Nianzhi asked quickly.

"Gene research is one of her majors. She uses her own egg cells to synthesize fertilized eggs and let other women give birth to surrogates, just like grabbing a mouse from a cage."

"Have you ever seen any experimenter put his feelings on the mice? Or treat the mice as human beings?"

Gu Nianzhi curled his lips and muttered; "I am also a guinea pig, but Qin Yaoguang uses me for experiments, so it is better to throw me into the orphanage. Why doesn't she use Wen Shouyi for experiments?"

Lu Jin felt a pain in her heart and didn't know how to comfort her for a while.

In a hurry, he subconsciously said: "...Maybe Wen Shouyi was the product of a failed experiment, so I didn't use her for the experiment."

Gu Nianzhi: "..."

Although I was not comforted, but my mood improved miraculously.

Gu Nianzhi still had a straight face and said solemnly: "It seems that I still have use value.

Lu Jin rubbed his hands in embarrassment, begging for mercy, and said, "...Read it, Dad knew it was wrong..."

Gu Nianzhi was embarrassed, and stepped forward to hold Lu Jin’s hand, took him to the sofa and sat down, and said, "Dad, I was just kidding. But..."

She rolled her eyes, "You mean, Qin Yaoguang started doing embryo genetic research long before I was born?"

This question can be answered.

Lu Jin said academically: "I have no concrete evidence, but since Wen Shouyi was born using this method, Qin Yaoguang must have done research in this area."

"At that time, she didn't ask me for advice, so I didn't know that she had been experimenting in this area."

In other words, Lu Jin knew nothing about Qin Yaoguang's secret experiment six years before Gu Nianzhi was born.

Gu Nianzhi nodded, and continued to ask curiously, "But why would she use her own egg cells and warm sperm to make fertilized eggs to conceive embryos? I thought she would use other people's egg cells for research."

Lu Jin smiled and said lightly: "If she had already had such an experiment, then she would definitely not be the first to do this experiment, and it would not be the last."

"What do you mean?" Gu Nianzhi's eyes suddenly lit up, "Could it be that she has done many research experiments in this area, even with other people's egg cells?"

"From the point of view of scientific experiments, that is certain."

Lu Jin patiently explained to her: "It takes a long time to do this kind of human embryo experiment. It usually takes seven months at the earliest from fertilization to the birth of the fetus, which means that premature babies are also included."

"Nine months is normal, plus pre- and post-preparations. One year has passed since the process of screening pregnant women and men."

"When an experiment takes a year from preparation to results, then the person doing the experiment will never do only one experiment at a time, do you know what I mean?"

Gu Nianzhi carefully digested the words of the approach in his mind, and after a while, he said thoughtfully: "What you mean is that doing this kind of experiment is no different from doing other biological experiments. Large batches of experiments are needed. In order to filter the effective results."

"She will prepare a lot of such fertilized eggs and transplant them into the belly of the pregnant mother to implant the pregnancy, and then observe the results."

Lu Jin focused his head, "This is the truth. The failure rate of experiments on biological genes is actually quite high. Therefore, she needs to accumulate numbers to achieve qualitative changes from quantitative changes."

"And to do so many experiments, Qin Yaoguang definitely can't just use her own egg cells." Lu Jin used a popular science tone to popularize Gu Nianzhi's common sense of egg cells.

"All mammalian females have immature egg cells in their ovaries when they are born."

"The number of female animal eggs is fixed at birth. It will not increase, but will gradually decrease."

"So it's impossible for Qin Yaoguang to use her own egg cells for this kind of large-scale experiment. She must have used other people's egg cells."

Gu Nianzhi completely understood, covering his mouth with his hand, and took a breath: "...oh my god! How many embryo experiments did Qin Yaoguang have done?! How many Wen Shouyi and Gu Nianzhi were born by her this way?! "

Lu Jin smiled bitterly, "Nianzhi, do you really think this kind of experiment is easy to succeed?"

"Do you think it is grafting seedlings?"

Gu Nianzhi: "..."

She really thought so!

"Is it... more difficult?" Gu Nianzhi's thick black eyelashes flickered, and his big eyes were full of curiosity.

"It's not more difficult, it's very difficult." Lu Jin didn't know how to explain to Gu Nianzhi, "I just checked Wen Shouyi's DNA sequence. I can see that Qin Yaoguang tried to gene-edit her but failed. "

Gu Nianzhi frowned, "That is to say, before she gave birth to me, she began to gene-edit the embryos, or is it for...what a disease?"

"Whether she let Wen Shouyi give birth to the disease at the beginning, I don't know, but that may be the prototype of her idea. From that time, she began to experiment with this method."

"But you have to know that human genes are very complex and huge. Decades ago, our understanding of genes was not as comprehensive as it is now, and the equipment and technical methods are not advanced."

"In that case, the embryo experiment, there are very few fertilized eggs that can successfully implant. It can be said that only one of a thousand fertilized eggs that have been genetically edited can successfully implant and allow the mother to conceive."

"And after these implanted fertilized eggs develop into embryos, they can be born smoothly. One in a hundred is amazing."

Gu Nianzhi was puzzled, "You mean, those embryos that are pregnant will abort?"

"Of course. And the chance of miscarriage is very high." Lu Jin sighed, "Because these embryos are genetically edited, many of them have genetic defects."

"The human body has a function of self-selection. An embryo with a genetic defect is called a congenital defect, and it will be aborted in its natural state, unless you use unconventional means to protect it."

"As far as scientific experiments are concerned, we will not protect embryos with congenital defects. Do you understand what I mean?-Very, very few children who have been successfully born and survived after gene editing. I doubt it. In Qin Yaoguang’s experiments, Wen Shouyi was probably the only embryo that was born and survived."

Gu Nianzhi nodded slowly and understood a little, but she had new questions.

"...You said that all embryos that have been gene-edited have congenital genetic defects. Then I...and Wen Shouyi, are the same?"

Lu Jin shook his head first, then nodded, and said, "You don't have one, Wen Shouyi does."

Gu Nianzhi: "..."

"Why didn't I?" Gu Nianzhi was very skeptical, "Dad, don't just say this to comfort me."

"I didn't comfort you. You are questioning my professional ability!" Lu Jin's eyes widened, "...you are the gene editing I did myself!"

"My approach is completely different from Qin Yaoguang. She disrupted the order of the original gene fragments and only cultivated the defective genes for He Zhichu."

"On the basis of your original genes, I excluded those non-human viral genes, and then expanded the expression with your own genes and added them."

"As a result of this, your genes have not been changed, but have been optimized to the maximum extent on the original basis."

Lu Jin couldn't help being proud: "Facts have proved that I succeeded. You have the first perfect set of genes in human history!-and on the basis of not changing your original genes!"

Gu Nianzhi: "@_@".

She started mosquito coil eyes again.

She knew every word Lu Jin said, but together she didn't understand it.

This is today's first update: Chapter 1748 "Gene Optimization".

Two more today.

Remind everyone of the monthly and recommended tickets.

Today is Monday, I highly recommend tickets!

The second shift at eight o'clock in the evening.

Meme da, big brothers and little angels~~~

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