I Have A Super USB Drive

In the end, only 33 of these fifty elderly people met the requirements of the experiment after physical examination and bone age test.

The remaining seventeen unqualified ones were naturally returned.

It is also fortunate that this Golob village can find so many elderly people over the age of fifty. I heard that in order to make up the number of people, the village chief even went to the neighboring village to negotiate with others.

The reason for the scarcity of elderly people is the lack of medical care. Fortunately, there are not many people in the village who can live to be over fifty.

Officials in Namibia have made statistics. In this country, more than 10% of children are orphans because their parents died of AIDS shortly after they gave birth.

In Namibia, the national population is only 2.58 million, but the HIV infection rate has reached 21.3%, which means that one-fifth of the people in this country are HIV carriers.

Fortunately, the HIV infection rate in Namibia is not too high in Africa, far less than Botswana's 37.3%, Swaziland's 38.8%, and Lesotho's 28.9%...

There are two world-famous specialties in Africa, one is diamonds and the other is AIDS.

Ignoring the dissatisfaction of Golob Village, Chen Chen directly let the thirty-three people take a bath, and then arranged for them to live in the basement, offering delicious food and drink, but restricting their activity area.

At the same time in the laboratory, Chen Chen recruited a group of experienced assistants to start cloning the cloned human embryos of the elderly.

In terms of specific operations, Chen Chen uses a more advanced three-dimensional polarization spindle imaging system. After positioning the egg cell nucleus, he uses a laser to punch a hole in the zona pellucida to remove the nucleus in a non-damaging mode. In order to use the micromanipulator to implant the somatic cell nucleus of the elderly.

Unfortunately, the technology of this group of people is completely incomparable to Chen Chen. They failed several times in the middle, and the process of using electric current and chemical induction also failed several times. In the end, all the clones were completed under the guidance of Chen Chen. Embryo.

Next, these cloned embryos need 14 days to grow to the blastocyst stage, and then the embryonic stem cells inside are extracted.

The reason why the international community opposes the cloning of human embryos is actually against this step. To some people, killing these fertilized eggs is equivalent to killing, which is ethically unacceptable.

Fortunately, these objections did not hinder the study of cloned embryos. So far, the technology of cloned embryonic stem cells in various countries is still making great strides forward.

After extracting embryonic stem cells, by controlling the growth environment of embryonic stem cells and manipulating the expression of specific genes, these embryonic stem cells can be differentiated into required hematopoietic stem cells and mesenchymal stem cells.

The stem cells cloned by this method have almost the same genes as those of the elderly, they will not have any rejection reaction, and they are very young stem cells.

After these old people have undergone chemotherapy and radiotherapy, they will be implanted into the human body to replace the already aging stem cells in the old people.

Once these young hematopoietic and mesenchymal stem cells return to the bone marrow, they will quickly differentiate into blood cells, muscle cells, liver cells, osteoblasts, adipocytes, chondrocytes, stroma and other human cells to repair and improve the body’s aging damage. .

This is the role of stem cells.

However, for a while, the academia has been caught in a huge misunderstanding, this misunderstanding was fermented by the earliest clone of the sheep Dolly——

As we all know, the cloned sheep Dolly is the world's earliest artificial cloned animal. Before Dolly was born, its donor was a Finnish Dorset white-faced sheep.

The experimenter extracted mammary gland cells from this sheep, and then took out the nucleus from the sheep, which cloned Dolly.

In other words, Dolly’s genes are basically the same as this Dorset white-faced sheep.

And this Finnish Dorset white-faced sheep was 6 years old when its mammary cells were extracted.

However, after the cloned sheep Dolly was born, it was discovered that Dolly’s telomeres were shorter than those of sheep of the same age.

Not only that, the cloned sheep Dolly had symptoms of premature aging at the age of 6. Although people took good care of it, Dolly eventually died.

In the same year, the Dorset white-faced sheep, the donor of the cloned sheep Dolly, died at the age of twelve.

In the research on lifespan in biology, the more mainstream theories are "telomere theory" and "free radical theory", both of which have not been thoroughly confirmed, but if telomeres are the key factor affecting lifespan, then cloned sheep Dolly Death seems to have a basis.

Because the nucleus donor of the cloned sheep Dolly is a six-year-old sheep, although the cloned Dolly goat is just born, the telomere length has actually been worn down to only six years of life?So it will die at the same time as the donor 6 years later?

This misunderstanding that year affected the entire academic community and cast a shadow over the entire cloning technology.

Because once this conclusion is true, it shows that most of the treatments developed by cloning technology are futile. No matter how to clone, the length of telomeres is as long as it is, and it will never change...

This misunderstanding even affected sci-fi works after 2000, causing many sci-fi works to set the short-lived defect for clones when they set up clones.

Fortunately, at the end of 2019, this misunderstanding was finally revealed-

In November 2019, Professor Li and his team of the Key Laboratory of Animal Reproductive Regulation and Breeding in Zhongzhou District reached a decisive conclusion in the study of telomeres in cloned animals:

After years of research, Professor Li and his team found that cloned embryos will undergo telomere reprogramming during the activation of the zygotic genome. Regardless of the length of the donor cell’s telomere, the reprogramming process can be restored to the original length, which is the donor. The length of itself!

Not only that, Professor Li also discovered that the length of telomeres is actually related to the development of cloned embryos.

During the cloning process, the telomeres of cloned embryos with normal development can be remarkably recovered, while for cloned embryos with abnormal development, the telomeres are not recovered, but shortened.

In addition, Professor Li also found that in the process of culturing cloned embryos, adding some small molecules such as trichomycin A, sodium butyrate, melatonin, etc., at the same time, can effectively improve the telomere under hypoxic environment. Reprogramming efficiency!

The results of this research were published in The FASEB Journal, the journal of the North American Federation of Experimental Biology Societies, and the title of the paper is "Inhibiting repressive promotes telomere in somatic cell reprogramming".

So far, the misunderstanding that the life span of cloned animals is limited by the donor has been completely broken.

As for why the cloned sheep Dolly had premature aging and why was the telomere length not enough?Then the benevolent sees the benevolent and the wise sees the wisdom.

While cultivating the cloned embryos of these elders in the laboratory, Dlamini finally sent the people on Chen Chen's list.

This time, Dlamini sent a total of 30 people, all of whom were elites, and Cheng Chao's trump card might not be prominent among them.

As long as Chen Chen can conquer these wolves-like mercenaries, the foundation for building a rapid reaction force in the future will be completely established.

Chen Chen's goal is to establish a private armed force capable of global precision strikes in the next few years. Its main purpose is to protect the company's property around the world and destroy any evidence against the company.