When a doctor opened a plug-in

Chapter 1660 Great Discovery! (Fifth more)

indeed!

Both Qi Kai and Yang Lan had question marks along the way.

I don't know why Chen Cang thinks this old fox is a good person!

How can he not look like a good person?

After Chen Cang came back, he said to the two of them: "Go, go back to the laboratory first, I have something to say!"

Qi Kai and Yang Lan nodded when they heard the sound. Although they didn't know what was going on,... they still followed.

Chen Cang has now given several solutions in the system!

Need to try.

But he is currently limited by one person and must work together with two people.

Fortunately, both of them are experienced seniors, and all experiments are done quickly!

It was the night that Tedanis left.

Chen Cang followed the system prompts and began to separate.

He found that as an intermediate product, Lewy bodies should be present in body fluid markers!

However, according to the special testing method, he found that it was not completely similar!

In this way...

Chen Cang suddenly said to Yang Lan and Qi Kai: "Actually... the Louis body is not a substance!"

"It should contain multiple substances, and we should look for common ground in cerebrospinal fluid, urine, and saliva!"

As soon as these words came out, the two of them immediately felt feasible and continued their crazy extraction and research.

Chen Cang now feels more and more that 5 days is too short!

However, on the fourth day!

The composition of Lewy bodies has been successfully deciphered: eosinophilic inclusion bodies composed of neurofilaments, tubulin, ubiquitin, and a special substance!

The discovery of this special substance made Chen Cang suddenly excited!

Because he discovered that this is a soluble protein expressed in the central nervous system presynaptic and pernuclear, and it is closely related to the pathogenesis and related dysfunction of Parkinson's disease.

This great discovery directly made everyone in the office ecstatic!

This is almost a milestone victory!

After the discovery of this special substance.

Chen Cang continued to start testing according to the system's auxiliary methods.

One after another special potential biomarker proteins have been discovered!

The most important is one, which is a special information symbol transmitted between neurotransmitters.

Everyone discovered that this turned out to be α-synuclein!

The discovery of α-synuclein has brought the experiment to a new stage.

Because, through the examination of body fluid marks, this substance was found in cerebrospinal fluid, saliva, and urine!

However, Chen Cang et al. discovered when conducting research.

The decrease of salivary secretion in Parkinson's rats seems to be related to the damage of α-synuclein and the innervation of the salivary gland autonomic nerve!

Afterwards!

Chen Cang immediately began to study Parkinson's patients with a single symptom, and found that this α-synuclein was suddenly found to be not simply a positive correlation!

For a while, it seems that the research on α-synuclein has reached a bottleneck again!

On the same day, Chen Cang discovered that when the rats were unable to provide research for their experiments, he contacted Wu Hui and sent the patient's blood directly!

Then, Chen Cang linked the words of Tedanis!

Perhaps Parkinson is not a degenerative disease.

After thinking of this possibility, Chen Cang suddenly found out.

This Tedanis is completely a liar.

Taidanis clearly wanted to bypass himself.

Because, after checking the results, Chen Cang found that:

Parkinson's disease is a neurodegenerative disease, but it is not a simple degenerative disease. A key feature of this disease is the accumulation of damaged α-synuclein in the body of Parkinson's disease patients.

So, how exactly is the damaged α-synuclein produced?

The tedious and boring scientific research made Chen Cang close to collapse!

During this period, Chen Cang basically had very little rest time every day in order not to waste every minute and every second.

It all depends on using potions to fight hard!

After Yang Lan and Qi Kai saw this scene, they had to admire it.

Perhaps Chen Cang's success was not accidental!

With this level of effort, coupled with excellent personal ability and talent, it is impossible to fail to achieve results!

Just when Chen Cang's experiment was at a deadlock.

Suddenly, Chen Cang had an idea and began to look up books to study the alpha-synuclein itself!

This research has really had some different effects.

That is, in general, α-synuclein is a normal substance.

But why does the number of t cells in the body increase?

What activated him?

Thinking of this, Chen Cang's mind began to run wildly.

Alpha-synuclein!

Parkinson!

t cell!

immune response!

...

All kinds of information kept mingling in my mind.

again and again!

Chen Cang began to speculate that normal α-synuclein is unlikely to cause the body's immune response?

Could it be...

Parkinson is actually an immune response?

In this way, the immune response generated by the accumulation of α-synuclein is like an autoimmune response?

Thinking of this, Chen Cang suddenly felt that this was terrible!

Next, he began to check information quickly!

Then through experiments, normal rats were injected with a large amount of extracted α-synuclein.

but……

no response!

This signaling factor did not cause a response in the rat nervous system.

T cells are normal!

Moreover, there was no response from Parkinson!

What's that?

At this time, within the last few hours of the system now.

Chen Cang suddenly discovered a special substance.

This substance is surprisingly similar to α-synuclein.

It's not alpha-synuclein!

Chen Cang hurriedly asked Yang Lan to come to help and conduct research!

This research.

Everyone was stunned!

Yang Lan was a little surprised and said: "Professor Chen, I said...you may be about to discover a miracle!"

Chen Cang was taken aback for a moment: "What's the matter?"

Qi Kai also stared wide-eyed, full of curiosity and expectation!

Yang Lan wrote the chemical equation of the object.

"This is a damaged α-synuclein, which can become folded α-synuclein!"

"This kind of thing is probably the kind of thing you mentioned that can induce cellular immune responses!"

After Chen Cang heard it, his eyes lit up!

He thought of all kinds of information, and suddenly said:

"Yes! Under normal circumstances, neurons have the ability to clear these abnormal α-synuclein!"

"However, when neurons are no longer able to clear abnormal alpha-synuclein, the autoimmune response in Parkinson's disease occurs."

"So, the alpha-synuclein in Lewy corpuscles is probably a broken alpha-synuclein!"

At this time, Chen Cang suddenly recalled the words of Taidanis!

He smiled slightly: "You now know that Professor Taidanis is not a bad person, right?"

Qi Kai and Yang Lan were taken aback.

Chen Cang said slowly: "Just as Taidanis said!"

"Parkinson's disease is partly an autoimmune disease!"

"And it is this folded α-synuclein that induces this immune disease!"

Chen Cang didn't say a word: that is...Tedanis may not know that Parkinson's is an autoimmune disease!

Otherwise, he would not tell himself the news.

...

...

ps: The arrival of the five shifts is late, thank you for your support.